AirCurve 11 ASV

Adaptive-Servo Ventilation device

 A bilevel PAP device with adaptive pressure support designed to stabilise breathing and personalise therapy for patients with central sleep apnea, obstructive sleep apnea, mixed apneas or periodic breathing. 

 

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Next-level support for patients and providers

Featuring a seamlessly integrated connected care system with enhanced support features and over-the-air updates, AirCurve 11 ASV* delivers a responsive adaptive servo-ventilation (ASV) algorithm.

It is designed to stabilise breathing2 in patients with central or mixed sleep apnea, or who have periodic breathing with or without obstructive events.

*ASV therapy is contraindicated in patients with chronic, symptomatic heart failure (NYHA 2-4) with reduced left ventricular ejection fraction (LVEF ≤ 45%) and moderate to severe predominant central sleep apnea.

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Most suitable for treating central sleep apnea

Standard therapies are often unable to fully normalise breathing for patients with pauses in breathing due to the absence of respiratory effort. AirCurve 11 ASV offers a simple solution to complex needs by combining the trusted algorithms of AirCurve™ 10 with Resmed Air11™ connected features. Offering a straightforward setup, the AirCurve 11 ASV’s algorithm has only four clinical settings. It comes with two modes: ASV with fixed EPAP and ASVAuto, which automatically adjusts the EPAP.

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Key features

  • AirView™
    Using AirView, providers can stay connected to patients, view invaluable insights and reports, manage patient records and troubleshoot remotely.
  • myAir™
    Through myAir, patients have access to Care Check-In and Personal Therapy Assistant to help them get started and stay on therapy.
  • ASVAuto mode
    Auto-adjusts EPAP to maintain upper airway patency and learns, predicts, responds to and optimises pressures to suit each patient’s own unique breathing pattern.
  • Easy-Breathe waveform
    Intelligently recreates a patient’s breathing pattern so breathing feels more natural.
  • Touchscreen
    Responsive and easy-to-use touchscreen makes navigating settings simple and intuitive.
  • Over-the-air updates
    Deliver features directly to the device, giving patients and providers access to the latest in PAP technology.

How the ASV 
algorithm works

Leveraging Breath Phase Mapping technology, the ASV algorithm dynamically adjusts inspiratory pressure support on a breath-by-breath basis in response to reductions in ventilation to help maintain ventilation near a target level. As breathing stabilises, pressure support gradually reduces toward a comfortable minimum level, helping mitigate hyperventilation and associated hypocapnia.

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Key elements of the algorithm

ASV and ASVAuto

1. Adaptive pressure support

Designed to counterbalance ventilatory instability, pressure support (PS) auto-adjusts between the Min PS and the Max PS to maintain each patient’s unique minute ventilation target (tidal volume and respiratory rate) while maintaining patient-device synchrony and comfort.

2. AutoEPAP (ASVAuto only)

Auto-adjusts expiratory positive airway pressure (EPAP) within the allowed range (Min EPAP and Max EPAP) to maintain upper airway patency.

3. Auto backup rate

Uses breath phase mapping to provide a timed backup rate synchronised with the patient’s own breathing to maintain the target minute ventilation in the case of apneas.

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How prevalent is central sleep apnea?

According to a very large observational analysis of Resmed’s American AirView database, which includes 133,000 patients receiving CPAP therapy, 3.5% of patients receiving CPAP therapy had emergent, transient or persistent central sleep apnea with central apnea index (CAI) >5.4

Transient CSA

CAI ≥ 5/h in week 1, < 5/h in week 13

Persistant CSA

CAI ≥ 5/h in week 1, ≥ 5/h in week 13

Emergent CSA

CAI < 5/h in week 1, ≥ 5/h in week 13

References

1

Resmed online survey of U.S. patients registered with myAir, conducted July-August 2022 (total N=97;question-level N=38-95). Data on file: eLB1708-37.

1

Resmed online survey of U.S. patients registered with myAir, conducted July-August 2022 (total N=97;question-level N=38-95). Data on file: eLB1708-37.

2

Aurora RN, Bista SR, Casey KR, et al. The Treatment of Central Sleep Apnea Syndromes in Adults: Practice Parameters with an Evidence-Based Literature Review and Meta-Analyses. JCSM 2016;12(5):757-761

3

Morgenthaler et al. Randomized controlled trial: The Complex Sleep Apnea Resolution Study: CPAP vs. ASV. Sleep 1999 (Abstract).

4

Liu et al. Trajectories of emergent central sleep apnoea during continuous positive airway pressure therapy. Chest. 2017; 152(4):751-60